The Magic of Our Mitochondria

Tucked away in your body’s cells, mitochondria convert the food you eat and the oxygen you breathe into energy. Each cell contains hundreds to thousands of mitochondria that are basically the cell’s power plant. Mitochondria have their own DNA and are passed along from mother to child. Mitochondria are also the often forgotten genome of our cells. Dr. Doug Wallace PhD, geneticist and evolutionary biologist and pioneer in mitochondrial research, concluded that dysfunctional mitochondria are the cause of 85% or more of our present day chronic diseases. If our mitochondria can’t meet the energy needs of our body, things start to fall apart, setting up a downward spiral that can eventually show up as diseases like obesity, heart disease, type 2 diabetes, cancer, autoimmune diseases, and Alzheimer’s disease, among many others. By maintaining or improving the health of your mitochondria, you can greatly improve health and longevity across many body systems and organs.

In most cells, mitochondria connect and disconnect in a constantly changing network that can adapt to various conditions. Mitochondria can fuse together and then divide again. Disruption of this fission-fusion dynamic can lead to health problems. Your genes play an important role in your health, as do your behaviors and your environment. Mitochondria are key players in the epigenetics of the DNA. Unlike genetic changes, epigenetic changes are reversible and do not change your DNA sequence, but they can change how your body reads a DNA sequence. In other words, mitochondria is the software system to our hardware DNA.

Our modern industrialized lifestyle contributes a great deal of stress on our mitochondria, and ultimately our gene expression. Humans are the only species that have created our own artificial environments in the name of progress and comfort. Since the great minds of Tesla and Edison, we are bombarded with artificial light, radio waves, TV signals, cell phone towers, 5G, wifi, etc. These new energies are foreign to our bodies and its epigenetics, and the mitochondria are responsible for adapting to these environmental stressors to keep us healthy. Simply put, healthy mitochondria = healthy person; unhealthy mitochondria = sickness/disease.

It is well known that as we age we have less energy. Now we know that it’s the mitochondria that are responsible for this decline in youthfulness. Every decade after 30 years of age, we lose the equivalence of 10% of our mitochondria. This state of heteroplasmy is when a percentage of the mitochondria in our cells are damaged or not efficient. In contrast, the state of good health of our mitochondria is called homoplasmy. Dr. Doug Wallace, PhD pioneered the use of  human mitochondrial DNA as a molecular marker, and he was the first to discover that the heteroplasmy rate was correlated to disease. He discovered that our mitochondria are passed on only from our mothers. His research led to the determination of a “Mitochondrial Eve” and 23 & Me and Ancestry.com both use his work to help determine our ancestral lineage. 

Dr. Nick Lane PhD, University College London, states in his epic book “Power, Sex, Suicide: Mitochondria and the Meaning of Life” the key to longevity is producing more mitochondria. He states this could potentially cure all diseases of old age at once. Because mitochondria accumulate in organs and tissues with a high need for energy, they are particularly important for muscles, and especially so for the heart. While aging is a complex process involving many physical changes, new advances in scientific discovery have brought a wealth of understanding about why we age, what cellular processes change with age, and the important role cellular health plays in how we age. Current evidence points to mitochondrial dysfunction as a factor commonly driving accelerated cellular aging.

Mitochondria also play an integral role in fat loss. This is one of the foundational principles of Liv24. We are committed to maximizing mitochondrial health by increasing your mitochondrial density and tuning up your existing mitochondria. By using circadian biology, light, and controlled cold exposure, we change your epigenetics to benefit the mitochondria for fat loss and longevity.

 

References:

Doug Wallace PhD, Mitochondria and the Future of Medicine: The Key to Understanding Disease, Chronic Illness, Aging, and Life Itself

Nick Lane PhD, Power, Sex, Suicide: Mitochondria and the Meaning of Life

https://pubmed.ncbi.nlm.nih.gov/29257072/ The Mitochondrial Basis of Aging and Age-Related Disorders

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685789/ Effects of obesity and weight loss on mitochondrial structure and function and implications for colorectal cancer risk

https://pubmed.ncbi.nlm.nih.gov/24818134/ Mitochondrial aging and age-related dysfunction of mitochondria